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Oncology
gastrointestinal malignancies
gallbladder cancer
A 44-year-old woman presents for a routine follow-up visit after a recent health screening that included an abdominal ultrasound. She reports no specific gastrointestinal symptoms, although she occasionally experiences mild, vague epigastric discomfort after large meals. Her medical history is otherwise unremarkable. During the physical examination, her vital signs are stable: temperature is 37.00C, blood pressure is 118/74 mmHg, pulse is 68/min, and respirations are 14/min. Abdominal palpation reveals no tenderness, and a Murphy's sign is negative. The previously obtained abdominal ultrasound indicated cholelithiasis, prompting a subsequent computed tomography (CT) scan for further characterization, which reveals a distinct hyperdense rim encasing the gallbladder. What is the most likely diagnosis and the definitive management strategy?
| Lab Parameter | Value | Reference Range |
|---|---|---|
| White Blood Cell Count (WBC) | 7.2 x 10^9/L | 4.5-11.0 x 10^9/L |
| Hemoglobin | 138 g/L | 120-150 g/L |
| Aspartate Aminotransferase (AST) | 25 U/L | 10-40 U/L |
| Alanine Aminotransferase (ALT) | 28 U/L | 7-56 U/L |
| Alkaline Phosphatase (ALP) | 85 U/L | 40-129 U/L |
| Total Bilirubin | 12 5mol/L | 3-17 5mol/L |

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